Ethnobotany, Chemistry, and Biological Activities of the Genus Tithonia (Asteraceae)
Identifieur interne : 001398 ( Main/Exploration ); précédent : 001397; suivant : 001399Ethnobotany, Chemistry, and Biological Activities of the Genus Tithonia (Asteraceae)
Auteurs : Daniela A. Chagas-Paula [Brésil] ; Rejane B. Oliveira [Brésil] ; Bruno A. Rocha [Brésil] ; Fernando B. Da Osta [Brésil]Source :
- Chemistry & Biodiversity [ 1612-1872 ] ; 2012-02.
English descriptors
- Teeft :
- Acoet, Acoet fraction, Active compounds, Aerial parts, Antifungal activities, Antimalarial, Antispasmodic, Antiviral, Assay, Biodiversity, Biological activities, Biological activity, Body weight, Chem, Chemistry biodiversity, Costa, Cytotoxic, Cytotoxicity, Derivative, Different extracts, Diversifolia, Diversifolia extracts, Diversifolin, Diversifolin ether, Ester, Ether, Ethnopharmacol, Etoh, Etoh extracts, Extract, Flavonoid, Fungi strains, Further studies, Genus, Genus tithonia, Haematological, Hepatic, Longiradiata, Major constituents, Meoh, Meoh extracts, Oliveira, Other species, Pedunculata, Petroleum ether fraction, Pharm, Pharmacological activities, Phytochemistry, Plant extracts, Resp, Rotundifolia, Significant decrease, Skeleton, Stls, Tagitinin, Tagitinins, Taxon, Thermal stimulus, Tirotundin, Tithonia, Tithonia extracts, Tithonia species, Toxicity, Tubaeformis, Wistar rats.
Abstract
The genus Tithonia is an important source of diverse natural products, particularly sesquiterpene lactones, diterpenes, and flavonoids. The collected information in this review attempts to summarize the recent developments in the ethnobotany, biological activities, and secondary metabolite chemistry of this genus. More than 100 structures of natural products from Tithonia are reported in this review. The species that has been most investigated in this genus is T. diversifolia, from which ca. 150 compounds were isolated. Biological studies are described to evaluate the anti‐inflammatory, analgesic, antimalarial, antiviral, antidiabetic, antidiarrhoeal, antimicrobial, antispasmodic, vasorelaxant, cancer‐chemopreventive, cytotoxic, toxicological, bioinsecticide, and repellent activities. A few of these studies have been carried out with isolated compounds from Tithonia species, but the majority has been conducted with different extracts. The relationship between the biological activity and the toxicity of compounds isolated from the plants of this genus as well as T. diversifolia extracts still remains unclear, and mechanisms of action remain to be determined.
Url:
DOI: 10.1002/cbdv.201100019
Affiliations:
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The collected information in this review attempts to summarize the recent developments in the ethnobotany, biological activities, and secondary metabolite chemistry of this genus. More than 100 structures of natural products from Tithonia are reported in this review. The species that has been most investigated in this genus is T. diversifolia, from which ca. 150 compounds were isolated. Biological studies are described to evaluate the anti‐inflammatory, analgesic, antimalarial, antiviral, antidiabetic, antidiarrhoeal, antimicrobial, antispasmodic, vasorelaxant, cancer‐chemopreventive, cytotoxic, toxicological, bioinsecticide, and repellent activities. A few of these studies have been carried out with isolated compounds from Tithonia species, but the majority has been conducted with different extracts. The relationship between the biological activity and the toxicity of compounds isolated from the plants of this genus as well as T. diversifolia extracts still remains unclear, and mechanisms of action remain to be determined.</div></front></TEI><affiliations><list><country><li>Brésil</li></country><region><li>État de São Paulo</li></region><settlement><li>São Paulo</li></settlement><orgName><li>Université de São Paulo</li></orgName></list><tree><country name="Brésil"><region name="État de São Paulo"><name sortKey="Chagas Aula, Daniela A" sort="Chagas Aula, Daniela A" uniqKey="Chagas Aula D" first="Daniela A." last="Chagas-Paula">Daniela A. Chagas-Paula</name></region><name sortKey="Da Osta, Fernando B" sort="Da Osta, Fernando B" uniqKey="Da Osta F" first="Fernando B." last="Da Osta">Fernando B. Da Osta</name><name sortKey="Da Osta, Fernando B" sort="Da Osta, Fernando B" uniqKey="Da Osta F" first="Fernando B." last="Da Osta">Fernando B. Da Osta</name><name sortKey="Da Osta, Fernando B" sort="Da Osta, Fernando B" uniqKey="Da Osta F" first="Fernando B." last="Da Osta">Fernando B. Da Osta</name><name sortKey="Oliveira, Rejane B" sort="Oliveira, Rejane B" uniqKey="Oliveira R" first="Rejane B." last="Oliveira">Rejane B. Oliveira</name><name sortKey="Rocha, Bruno A" sort="Rocha, Bruno A" uniqKey="Rocha B" first="Bruno A." last="Rocha">Bruno A. Rocha</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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